product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
LY 450139
catalog :
6559/5
quantity :
5 mg (also 25 mg)
price :
94 USD
more info or order :
image
image 1 :
Tocris Bioscience 6559/5 image 1
Cat.No. 6559 - LY 450139 C19H27N3O4 CAS No. 425386-60-3
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
6559
SKU :
6559/5
product name :
LY 450139
description :
-secretase pseudo-inhibitor
target :
gamma-Secretase Modulators
unit size :
5 mg (also 25 mg)
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
361.44
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
LY 450139 is a -secretase pseudo-inhibitor. Inhibits A secretion from cells in vitro and increases accumulation of -secretase products and long A species in vitro and in vivo . Also attenuates the accumulation of activated microglia and neurological injury in a traumatic brain injury animal model.
product keywords :
LY450139 Semagacestat gamma secretase inhibitor inhibits amyloid beta secretion Abeta Gamma-Secretase 6559, -Secretase, g-Secretase, gamma Secretase
extended description :
-secretase pseudo-inhibitor
chemical name text :
(2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide
formula :
C19H27N3O4
formula text :
C19H27N3O4
cas num :
425386-60-3
USD :
104
USD 2025 :
94 USD
product details :
-secretase pseudo-inhibitor
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK