CP 43 | Tocris Bioscience 6558 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CP 43

catalog :

6558

quantity :

10 mg (also 50 mg)

price :

187 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6558

SKU :

6558/10

product name :

CP 43

description :

Potent TAOK inhibitor

target :

Other Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

384.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent TAO kinase (TAOK) inhibitor (IC50 values are 11 nM/L and 15 nM/L for TAOK1 and TAOK2, respectively). Inhibits TAOK phosphorylation and activation of JNK in vitro . Prolongs duration of mitosis and increases mitotic cell death in the SKBR3 breast cancer cell line. Also reduces tau phopshorylation in cortical neurons at sites associated with neurodegeneration in human tauopathies.

catalog number base :

6558

product keywords :

CP43 TAOK TAOK1 TAOK2 TAO thousand and one amino acid kinase inhibitors inhibits potent JNK activation Other Kinases JNK/c-jun 6558,

extended description :

Potent TAOK inhibitor

chemical name text :

N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1 -biphenyl]-4-carboxamide

formula :

C 25 H 24 N 2 O 2

formula text :

C25H24N2O2

cas num :

850467-66-2

2020 USD :

181

2021 USD :

187 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage