product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
OB-1
catalog :
6545/10
quantity :
10 mg (also 50 mg)
price :
173 USD
more info or order :
image
image 1 :
Tocris Bioscience 6545/10 image 1
Cat.No. 6545 - OB-1 C21H17N3O6 CAS No. 300803-69-4
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
6545
SKU :
6545/10
product name :
OB-1
description :
Stomatin-like protein-3 (STOML3) oligomerization inhibitor
target :
Other Piezo Channel Compounds
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
98%
storage :
Store at RT
observed molecular weight :
407.38
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
OB-1 is a stomatin-like protein-3 (STOML3) oligomerization inhibitor. Reduces STOML3 cluster size in the plasma membrane. Decreases mechanically-induced Piezo1 but not ASIC3 current amplitudes in N2a cells and cultured mouse sensory neurons in vitro . Subcutaneous administration in mice reversibly silences touch receptor activity and inhibits paw withdrawal reflex in a mouse neuropathic pain model.
product keywords :
OB1 Stomatin-like protein-3 oligomerization inhibitors inhibits mechanosensitive allodynia neuropathic pain Piezo1 STOML3 Piezo Channels 6545,
extended description :
Stomatin-like protein-3 (STOML3) oligomerization inhibitor
chemical name text :
Ethyl 5-(1-methyl-4-nitro-1H-imidazol-5-yloxy)-2-phenylbenzofuran-3-carboxylate
formula :
C21H17N3O6
formula text :
C21H17N3O6
cas num :
300803-69-4
USD :
171
USD 2025 :
173 USD
product details :
Stomatin-like protein-3 (STOML3) oligomerization inhibitor
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK