AZD 2098 | Tocris Bioscience 6541 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZD 2098

catalog :

6541

quantity :

10 mg (also 50 mg)

price :

223 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6541

SKU :

6541/10

product name :

AZD 2098

description :

Potent and selective CCR4 antagonist

target :

Chemokine Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

334.18

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective CCR4 antagonist (pIC50 = 7.8). Exhibits no activity at CXCR1 and CXCR2, CCR1, CCR2b, CCR5, CCR7, and CCR8 at 10 M, and no significant activity when screened against a panel of 120 receptors and enzymes. Inhibits CCL22 Ca2+ response and Th2 cell CCL17/22 driven chemotaxis in vitro . Inhibits lung inflammation following antigen challenge in ovalbumin- sensitized rats.

catalog number base :

6541

product keywords :

AZD2098 potent selective CCR4 chemokines receptors antagonists antagonism chemotaxis Chemokine CC Receptors 6541,

extended description :

Potent and selective CCR4 antagonist

chemical name text :

2,3-Dichloro-N-(3-methoxy-2-pyrazinyl)benzenesulfonamide

formula :

C 11 H 9 Cl 2 N 3 O 3 S

formula text :

C11H9Cl2N3O3S

cas num :

566203-88-1

2020 USD :

216

2021 USD :

223 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage