PF 04449913 maleate | Tocris Bioscience 6538/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 04449913 maleate

catalog :

6538/5

quantity :

5 mg (also 25 mg)

price :

97 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6538 - PF 04449913 maleate C21H22N6O.C4H4O4 CAS No. 2030410-25-2

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6538

SKU :

6538/5

product name :

PF 04449913 maleate

description :

Potent Smo antagonist

target :

Smoothened Receptor Antagonists

unit size :

5 mg (also 25 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

490.51

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PF 04449913 maleate is a potent Smo antagonist (IC50 = 5 nM). Attenuates the leukemia-initiation potential of AML cells in a serial transplantation mouse model. Also eliminates self-propagation capacity of AML cells.

product keywords :

PF04449913 maleate potent Smo antagonists antagonizes antagonism AML PF913 glasdegib PF-913 Smoothened Receptors Hedgehog Signaling Cancer Stem Cells 6538,

extended description :

Potent Smo antagonist

chemical name text :

1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt

formula :

C21H22N6O.C4H4O4

formula text :

C21H22N6O.C4H4O4

cas num :

2030410-25-2

USD :

107

USD 2025 :

97 USD

product details :

Potent Smo antagonist

alt names :

glasdegib,PF-913

more info or order :

Tocris Bioscience product webpage