NVP 2 | Tocris Bioscience 6535 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NVP 2

catalog :

6535

quantity :

5 mg

price :

238 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6535

SKU :

6535/5

product name :

NVP 2

description :

Potent and selective ATP-competitive CDK9 inhibitor

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

97%

observed molecular weight :

513.07

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective ATP-competitive CDK9 inhibitor (IC50 = 0.5 nM). Exhibits selectivity for CDK9 over a panel of 468 kinases, but inhibits DYRK1B (IC50 = 350 nM), displays 90% binding to CDK7 (IC50 10 M) and CDK13. Inhibits proliferation of MOLT4 cells in vitro . Induces apoptosis.

catalog number base :

6535

product keywords :

NVP2 Cyclin-dependent protein kinases inhibitors inhibits Cdk9 potent selective Cyclin-dependent Kinase 6535,

extended description :

Potent and selective ATP-competitive CDK9 inhibitor

chemical name text :

4-[[[5 -Chloro-2 -[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4 -bipyridin]-6-yl]amino]methyl]tetrahydro-2H-pyran-4-carbonitrile

formula :

C 27 H 37 ClN 6 O 2

formula text :

C27H37ClN6O2

cas num :

1263373-43-8

2020 USD :

228

2021 USD :

238 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage