TH 5427 hydrochloride | Tocris Bioscience 6534 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TH 5427 hydrochloride

catalog :

6534

quantity :

10 mg (also 50 mg)

price :

153 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6534

SKU :

6534/10

product name :

TH 5427 hydrochloride

description :

Potent NUDT5 inhibitor

target :

Hydrolase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

527.79

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent nudix hydrolase 5 (NUDT5) inhibitor (IC50 = 29 nM). Displays 650-fold selectivity for NUDT5 over MTH1. Inhibits ATP synthesis, chromatin remodeling, gene expression and proliferation in progestin-treated breast cancer cells in vitro .

catalog number base :

6534

product keywords :

TH5427 HCl nudix hydrolase 5 inhibitors inhibits potent selective NUDT5 breast cancer proliferation Other Hydrolases 6534,

extended description :

Potent NUDT5 inhibitor

chemical name text :

7-[[5-(3,4-Dichlorophenyl)-1,3,4-oxadiazol-2-yl]methyl]-1,3-dimethyl-8-(piperazine-1-yl)-1H-purine-2,6-dione hydrochloride

formula :

C 20 H 20 Cl 2 N 8 O 3 .HCl

formula text :

C20H20Cl2N8O3.HCl

2020 USD :

150

2021 USD :

153 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage