product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SGC AAK1 1
catalog :
6528/5
quantity :
5 mg (also 25 mg)
price :
115 USD
more info or order :
citations: 1
Reference
Puray Chavez M, Lapak K, Schrank T, Elliott J, Bhatt D, Agajanian M, et al. Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell. Cell Rep. 2021;36:109364 pubmed publisher
image
image 1 :
Tocris Bioscience 6528/5 image 1
Cat.No. 6528 - SGC AAK1 1 C21H25N5O3S CAS No. 2247894-32-0
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
6528
SKU :
6528/5
product name :
SGC AAK1 1
description :
AAK1 and BMP2K inhibitor; activates Wnt signaling
target :
Other Kinase Inhibitors
unit size :
5 mg (also 25 mg)
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
427.52
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SGC AAK1 1 is an adaptor-associated protein kinase 1 (AAK1) and BMP-2-inducible protein kinase (BMP2K) inhibitor (IC50 values are 233 nM and 1.48 M for AAK1 and BMP2K, respectively). Inhibits AAK1-dependent phosphorylation of AP2M1. Activates Wnt signaling.
product keywords :
SGCAAK11 AAK1 BMP2K inhibitors inhibits WNT signaling activators activates BMP-2-inducible protein kinase Adaptor-associated protein kinase 1 Other Kinases Other Wnt Signaling 6528,
extended description :
AAK1 and BMP2K inhibitor; activates Wnt signaling
chemical name text :
N-(6-(3-((N,N-diethylsulfamoyl)amino)phenyl)-1H-indazol-3-yl)cyclopropanecarboxamide
formula :
C21H25N5O3S
formula text :
C21H25N5O3S
cas num :
2247894-32-0
USD :
111
USD 2025 :
115 USD
product details :
AAK1 and BMP2K inhibitor; activates Wnt signaling
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK