Dynarrestin | Tocris Bioscience 6526/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Dynarrestin

catalog :

6526/5

quantity :

5 mg

price :

327 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Shaiken T, Grimm S, Siam M, Williams A, Rezaeian A, Kraushaar D, et al. Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix. iScience. 2023;26:105965 pubmed publisher
Zhovmer A, Manning A, Smith C, Hayes J, Burnette D, Wang J, et al. Mechanical Counterbalance of Kinesin and Dynein Motors in a Microtubular Network Regulates Cell Mechanics, 3D Architecture, and Mechanosensing. ACS Nano. 2021;15:17528-17548 pubmed publisher
Zhou Y, Su J, Samuel C, Ma D. Measles Virus Forms Inclusion Bodies with Properties of Liquid Organelles. J Virol. 2019;93: pubmed publisher

image

image 1 :

Cat.No. 6526 - Dynarrestin C22H23F2N3O2S CAS No. 2222768-84-3

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6526

SKU :

6526/5

product name :

Dynarrestin

description :

Inhibitor of Hedgehog (Hh) signaling; inhibits cytoplasmic dynein

target :

Hedgehog Signaling Inhibitors

unit size :

5 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

431.5

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dynarrestin is a dynein inhibitor. Inhibits hedgehog signaling in vitro (IC50 = 0.22 M). Exhibits reversible inhibition of cytoplasmic dynein 1-dependent microtubule binding and cytoplasmic dynein 2-dependent intraflagellar transport. Inhibits tumor cell proliferation in a mouse medulloblastoma model.

product keywords :

Dynarrestin hedgehog Hh signaling inhibitors inhibits dynein cytoplasmic Hedgehog Signaling 6526,

extended description :

Inhibitor of Hedgehog (Hh) signaling; inhibits cytoplasmic dynein

chemical name text :

Ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate

formula :

C22H23F2N3O2S

formula text :

C22H23F2N3O2S

cas num :

2222768-84-3

USD :

323

USD 2025 :

327 USD

product details :

Inhibitor of Hedgehog (Hh) signaling; inhibits cytoplasmic dynein

more info or order :

Tocris Bioscience product webpage