TL 12-186 | Tocris Bioscience 6524 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TL 12-186

catalog :

6524

quantity :

5 mg

price :

371 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6524

SKU :

6524/5

product name :

TL 12-186

description :

Multikinase degrading PROTAC

target :

Active Degraders

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

931.46

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PROTAC comprised of a highly promiscuous kinase inhibitor conjugated to the cereblon E3 ubiquitin ligase ligand, pomalidomide (Cat. No. 6302). Degrades a range of kinases in MOLT-4 and MOLM-14 cell lines. . Negative control TL 13-27 (Cat. No. 6525) is also available. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

catalog number base :

6524

product keywords :

TL12-186 PROTAC PROTACs Proteolysis targeted chimeras cereblon E3 ubiquitin ligase kinase targeted protein degradation tpd active degraders degrades Active Degraders Other Kinases 6524, target protein knockdown, PROTAC, SNIPER

extended description :

Multikinase degrading PROTAC

chemical name text :

N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamide

formula :

C 44 H 51 ClN 10 O 9 S

formula text :

C44H51ClN10O9S

cas num :

2250025-88-6

2020 USD :

363

2021 USD :

371 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage