TL 12-186 | Tocris Bioscience 6524/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TL 12-186

catalog :

6524/5

quantity :

5 mg

price :

452 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6524 - TL 12-186 C44H51ClN10O9S CAS No. 2250025-88-6

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6524

SKU :

6524/5

product name :

TL 12-186

description :

Multikinase Degrader (PROTAC )

target :

Active Degraders

unit size :

5 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

931.46

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TL 12-186 is a degrader (PROTAC ) comprised of a highly promiscuous kinase inhibitor conjugated to the cereblon E3 ubiquitin ligase ligand, pomalidomide (Cat. No. 6302). Degrades a range of kinases in MOLT-4 and MOLM-14 cell lines. . Negative control TL 13-27 (Cat. No. 6525) is also available. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

product keywords :

TL12-186 PROTAC PROTACs Proteolysis targeted chimeras cereblon E3 ubiquitin ligase kinase targeted protein degradation tpd active degraders degrades Other Kinases Kinase Degraders 6524, target protein knockdown, PROTAC, SNIPER

extended description :

Multikinase Degrader (PROTAC )

chemical name text :

N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamide

formula :

C44H51ClN10O9S

formula text :

C44H51ClN10O9S

cas num :

2250025-88-6

USD :

438

USD 2025 :

452 USD

product details :

Multikinase Degrader (PROTAC )

more info or order :

Tocris Bioscience product webpage