EPZ 015666 | Tocris Bioscience 6516 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

EPZ 015666

catalog :

6516

quantity :

25 mg

price :

649 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6516

SKU :

6516/25

product name :

EPZ 015666

description :

Potent and selective PRMT5 inhibitor

target :

Protein Arginine Methyltransferase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

383.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50 = 22 nM, Ki = 5 nM). Displays selectivity for PRMT5 over a panel of 20 other protein methyltransferases. Exhibits dose-dependent antitumor effects in multiple mantle cell lymphoma (MCL) xenograft models. Orally bioavailable.

catalog number base :

6516

product keywords :

EPZ015666 GSK3235025 potent selective PRMT5 protein arginine methytransferase 5 inhibitors inhibits Protein Arginine Methyltransferases 6516,

extended description :

Potent and selective PRMT5 inhibitor

chemical name text :

N-[(2S)-3-(3,4-Dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)-4-pyrimidinecarboxamide

formula :

C 20 H 25 N 5 O 3

formula text :

C20H25N5O3

cas num :

1616391-65-1

2020 USD :

624

2021 USD :

649 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage