YM 155 | Tocris Bioscience 6491/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

YM 155

catalog :

6491/10

quantity :

10 mg (also 50 mg)

price :

157 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Serafini R, Frere J, Zimering J, Giosan I, Pryce K, Golynker I, et al. SARS-CoV-2 airway infection results in the development of somatosensory abnormalities in a hamster model. Sci Signal. 2023;16:eade4984 pubmed publisher
Latifkar A, Ling L, Hingorani A, Johansen E, Clement A, Zhang X, et al. Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity. Dev Cell. 2019;49:393-408.e7 pubmed publisher

image

image 1 :

Cat.No. 6491 - YM 155 C20H19BrN4O3 CAS No. 781661-94-7

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6491

SKU :

6491/10

product name :

YM 155

description :

Survivin suppressor

target :

IAP Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

443.29

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

YM 155 is a survivin suppressor. Down-regulates survivin expression and sensitizes human NSCLC cell lines to radiation. Enhances radiation-induced tumor regression in nude mice bearing NSCLC xenografts. Also induces apoptosis in TRAIL-resistant glioma cells in vitro . YM 155 is also an inhibitor of ILF3 (interleukin enhancer binding factor 3), an RNA-binding protein. It reduces thermal and mechanical hypersensitivity in a mice model of inflammatory pain.

product keywords :

YM155 survivin suppressor inhibits inhibitors induces apoptosis sepantronium bromide ILF3 interleukin enhancer binding factor 3 inflammatory pain sepantronium bromide Inhibitor of Apoptosis (IAP) DNA, RNA and Protein Synthesis 6491,

extended description :

Survivin suppressor

chemical name text :

4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide

formula :

C20H19BrN4O3

formula text :

C20H19BrN4O3

cas num :

781661-94-7

USD :

155

USD 2025 :

157 USD

product details :

Survivin suppressor

alt names :

sepantronium bromide

more info or order :

Tocris Bioscience product webpage