Terbinafine hydrochloride | Tocris Bioscience 6484/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Terbinafine hydrochloride

catalog :

6484/50

quantity :

50 mg (also 250 mg)

price :

52 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gurges P, Liu H, Horner R. Modulation of TASK-1/3 channels at the hypoglossal motoneuron pool and effects on tongue motor output and responses to excitatory inputs in vivo: implications for strategies for obstructive sleep apnea pharmacotherapy. Sleep. 2021;44: pubmed publisher

image

image 1 :

Cat.No. 6484 - Terbinafine hydrochloride C21H25N.HCl CAS No. 78628-80-5

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

6484

SKU :

6484/50

product name :

Terbinafine hydrochloride

description :

Selective K2P9.1 (TASK-3) activator; also inhibits fungal squalene epoxidase

target :

Two-P Potassium Channels Activators

unit size :

50 mg (also 250 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

327.89

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Terbinafine hydrochloride is a selective TASK3 activator (pEC50 = 6.2). Exhibits 10-fold selectivity for TASK3 over TREK2, TRESK, THIK1 and TASK2. Also inhibits TWIK1 (pIC50 = 5.69). Also antifungal; inhibits fungal sterol biosynthesis by inhibition of squalene epoxidase.

product keywords :

K2P selective TASK3 activators activates squalene epoxidase monooxygenase inhibitors inhibits antifungal antimycotic Two-P Potassium Channels Other Oxygenases/Oxidases Antifungals 6484,

extended description :

Selective K2P9.1 (TASK-3) activator; also inhibits fungal squalene epoxidase

chemical name text :

N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine hydrochloride

formula :

C21H25N.HCl

formula text :

C21H25N.HCl

cas num :

78628-80-5

USD :

USD 2025 :

52 USD

product details :

Selective K2P9.1 (TASK-3) activator; also inhibits fungal squalene epoxidase

more info or order :

Tocris Bioscience product webpage