XMU MP 1 | Tocris Bioscience 6482 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

XMU MP 1

catalog :

6482

quantity :

10 mg (also 50 mg)

price :

272 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Turunen S, von Nandelstadh P, Ohman T, Gucciardo E, Seashore Ludlow B, Martins B, et al. FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis. Cell Death Differ. 2019;: pubmed publisher

product information

brand :

Tocris

master code :

6482

SKU :

6482/10

product name :

XMU MP 1

description :

Potent and selective MST1/2 inhibitor; orally bioavailable

target :

Other Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

416.48

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective ATP-competitive mammalian sterile 20-like kinase (MST) 1/2 inhibitor (IC50 values are 38.1 and 71.1 nM for MST2 and MST1, respectively). Enhances activity of downstream YAP in vitro . Augments mouse intestinal repair and promotes liver repair and regeneration in a mouse model of acute and chronic liver injury. Orally bioavailable.

catalog number base :

6482

product keywords :

XMUMP1 potent selective MST1 MST2 Inhibitors inhibits tissue regeneration liver repair orally bioavailable mammalian sterile 20-like kinase Ste20 Hippo/Yap signaling Other Kinases 6482,

extended description :

Potent and selective MST1/2 inhibitor; orally bioavailable

chemical name text :

4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide

formula :

C 17 H 16 N 6 O 3 S 2

formula text :

C17H16N6O3S2

cas num :

2061980-01-4

2020 USD :

266

2021 USD :

272 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage