6475/5 | Tocris Bioscience 6475/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6475/5

catalog :

6475/5

quantity :

5 mg (also 25 mg)

price :

133 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Chmielarz P, Er x, Konovalova J, Bandres L, Hlushchuk I, Albert K, et al. GDNF/RET Signaling Pathway Activation Eliminates Lewy Body Pathology in Midbrain Dopamine Neurons. Mov Disord. 2020;35:2279-2289 pubmed publisher

image

image 1 :

Cat.No. 6475 - SU 6656 C19H21N3O3S CAS No. 330161-87-0

product information

master code :

6475

SKU :

6475/5

product name :

SU 6656

unit size :

5 mg (also 25 mg)

description :

Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable

target :

Src Family Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

371.45

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SU 6656 is a potent ATP-competitive Src family kinase inhibitor (IC50 values are 0.02, 0.13, 0.17, 0.28 and 6.88 nM for Yes, Lyn, Fyn, Src and Lck, respectively). Exhibits 6.5 fold selectivity for Src family over other kinases. Also AMPK inhibitor (IC50 = 0.22 M for the 2 kinase domain). Cell permeable.

top caption :

Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable

extended description :

Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable

chemical name text :

2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide

formula :

C19H21N3O3S

formula text :

C19H21N3O3S

cas num :

330161-87-0

USD :

133 USD

product details :

Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage