6471/100 | Tocris Bioscience 6471/100 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6471/100

catalog :

6471/100

quantity :

100 mg

price :

665 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Schwalm M, Berger L, Meuter M, Vasta J, Corona C, R xf6 hm S, et al. A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins. Front Cell Dev Biol. 2022;10:886537 pubmed publisher
Pierozan P, Jernerén F, Karlsson O. Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells. Arch Toxicol. 2018;92:1729-1739 pubmed publisher

image

image 1 :

Cat.No. 6471 - A 410099.1, amine C32H49N5O5.HCl CAS No. 2374122-37-7

product information

master code :

6471

SKU :

6471/100

product name :

A 410099.1, amine

unit size :

100 mg

description :

Functionalized IAP ligand for PROTACs

target :

Degrader Building Blocks

category :

Small Molecules

purity :

98%

observed molecular weight :

620.22

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

A 410099.1, amine is a functionalized IAP ligand for PROTAC research and development. Boc protected A 410099.1 (Cat.No. 6470). Supplied with an amine functional handle for ready conjugation to a linker/target protein ligand. NanoBRET assays show EC50 values of 4.6, 9.2 and 15.6 nM for cIAP1, cIAP2 and XIAP proteins, respectively. Part of a range of functionalized tool molecules for PROTAC R D. . Please contact us for SD files of our available Degrader Building Blocks. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

top caption :

Functionalized IAP ligand for PROTACs

extended description :

Functionalized IAP ligand for PROTACs

chemical name text :

tert-Butyl [(S)-1-[[(S)-2-[(2S,4S)-4-amino-2-[[(R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl](methyl)carbamate hydrochloride

formula :

C32H49N5O5.HCl

formula text :

C32H49N5O5.HCl

cas num :

2374122-37-7

USD :

665 USD

product details :

Functionalized IAP ligand for PROTACs

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage