TC E3 5031 | Tocris Bioscience 6466 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC E3 5031

catalog :

6466

quantity :

100 mg

price :

439 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6466

SKU :

6466/100

product name :

TC E3 5031

description :

Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

unit size :

100 mg

purity :

98%

observed molecular weight :

332.26

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Derivative of Thalidomide (Cat.No. 0652), commonly used as a precursor to PROTAC that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with a carboxylic acid functional handle at a position known not to significantly affect binding to cereblon, for ready conjugation to a linker/target protein ligand. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. . Require a different derivative? Get in touch .

catalog number base :

6466

product keywords :

PROTACs thalidomide PROteolysis TArgeting Chimeras cereblon E3 ligase ligand 3 TCE35031 Functionalized E3 Ligase Ligands 6466,

extended description :

Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs

chemical name text :

2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid

formula :

C 15 H 12 N 2 O 7

formula text :

C15H12N2O7

cas num :

1061605-21-7

2020 USD :

426

2021 USD :

439 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage