6466/100 | Tocris Bioscience 6466/100 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6466/100

catalog :

6466/100

quantity :

100 mg

price :

535 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6466 - TC E3 5031 C15H12N2O7 CAS No. 1061605-21-7

product information

master code :

6466

SKU :

6466/100

product name :

Thalidomide-4-hydroxyacetate

unit size :

100 mg

description :

Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs

target :

Degrader Building Blocks

category :

Small Molecules

purity :

98%

observed molecular weight :

332.26

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Thalidomide-4-hydroxyacetate is a derivative of Thalidomide (Cat.No. 0652), commonly used as a precursor to PROTAC that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with a carboxylic acid functional handle at a position known not to significantly affect binding to cereblon, for ready conjugation to a linker/target protein ligand. . Thalidomide-4-hydroxyacetate has been recently renamed. The previous name for this product was TC E3 5031. . Please contact us for SD files of our available Degrader Building Blocks. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. . Require a different derivative? Get in touch .

top caption :

Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs

extended description :

Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs

chemical name text :

2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid

formula :

C15H12N2O7

formula text :

C15H12N2O7

cas num :

1061605-21-7

USD :

535 USD

product details :

Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage