6462/100 | Tocris Bioscience 6462/100 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6462/100

catalog :

6462/100

quantity :

100 mg

price :

585 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Smalley J, Adams G, Millard C, Song Y, Norris J, Schwabe J, et al. PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes. Chem Commun (Camb). 2020;56:4476-4479 pubmed publisher

image

image 1 :

Cat.No. 6462 - VH 032, amine C22H30N4O3S.2HCl CAS No. 2137142-47-1

product information

master code :

6462

SKU :

6462/100

product name :

VH 032, amine

unit size :

100 mg

description :

Functionalized VHL ligand for PROTACs

target :

Degrader Building Blocks

category :

Small Molecules

purity :

98%

observed molecular weight :

503.49

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

VH 032, amine is a derivative of the von Hippel-Lindau (VHL) ligand, VH 032; commonly used as a precursor to a PROTAC that hijacks VHL as the E3 ubiquitin ligase component. Supplied with a primary amine functional handle at a position known not to significantly affect binding to VHL, for ready conjugation to a linker/target protein ligand. . Please contact us for SD files of our available Degrader Building Blocks. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. . Require a different derivative? Get in touch

top caption :

Functionalized VHL ligand for PROTACs

extended description :

Functionalized VHL ligand for PROTACs

chemical name text :

(4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide dihydrochloride

formula :

C22H30N4O3S.2HCl

formula text :

C22H30N4O3S.2HCl

cas num :

2137142-47-1

USD :

585 USD

product details :

Functionalized VHL ligand for PROTACs

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage