JNJ 0966 | Tocris Bioscience 6439 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JNJ 0966

catalog :

6439

quantity :

10 mg (also 50 mg)

price :

179 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6439

SKU :

6439/10

product name :

JNJ 0966

description :

Pro-MMP9 activation inhibitor

target :

Synthetic Metalloprotease Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

360.45

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Pro-MMP9 activation inhibitor (IC50 = 440 nM). Inhibits the conversion of pro-MMP9 to active MMP9, without directly affecting MMP9 enzymatic activity. Exhibits selectivity for pro-MMP9 over pro-MMP1, 2 and 3. Inhibits cell invasion in in vitro assays. Reduces motor impairment in a mouse EAE model. Brain penetrant.

catalog number base :

6439

product keywords :

JNJ0966 Pro-MMP9 activation inhibitor zymogen MMP9 signaling brain penetrant cell invasion EAE experimental autoimmune encephalomyelitis matrix metalloprotease Matrix Metalloprotease 6439,

extended description :

Pro-MMP9 activation inhibitor

chemical name text :

N-[2-[(2-Methoxyphenyl)amino]-4 -methyl[4,5 -bithiazol]-2 -yl]acetamide

formula :

C 16 H 16 N 4 O 2 S 2

formula text :

C16H16N4O2S2

cas num :

315705-75-0

2020 USD :

173

2021 USD :

179 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage