6439/10 | Tocris Bioscience 6439/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6439/10

catalog :

6439/10

quantity :

10 mg (also 50 mg)

price :

225 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6439 - JNJ 0966 C16H16N4O2S2 CAS No. 315705-75-0

product information

master code :

6439

SKU :

6439/10

product name :

JNJ 0966

unit size :

10 mg (also 50 mg)

description :

Pro-MMP9 activation inhibitor

target :

Synthetic Metalloprotease Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

360.45

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JNJ 0966 is a pro-MMP9 activation inhibitor (IC50 = 440 nM). Inhibits the conversion of pro-MMP9 to active MMP9, without directly affecting MMP9 enzymatic activity. Exhibits selectivity for pro-MMP9 over pro-MMP1, 2 and 3. Inhibits cell invasion in in vitro assays. Reduces motor impairment in a mouse EAE model. Brain penetrant.

top caption :

Pro-MMP9 activation inhibitor

extended description :

Pro-MMP9 activation inhibitor

chemical name text :

N-[2-[(2-Methoxyphenyl)amino]-4 -methyl[4,5 -bithiazol]-2 -yl]acetamide

formula :

C16H16N4O2S2

formula text :

C16H16N4O2S2

cas num :

315705-75-0

USD :

225 USD

product details :

Pro-MMP9 activation inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage