BRD 6989 | Tocris Bioscience 6438 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BRD 6989

catalog :

6438

quantity :

10 mg (also 50 mg)

price :

133 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6438

SKU :

6438/10

product name :

BRD 6989

description :

Cdk8 inhibitor; enhances IL-10 production

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

264.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Binds and inhibits Cdk8 in complex with cyclin C (IC50 200 nM). Enhances IL-10 production in activated human and murine macrophages and dendritic cells (EC50 is approximately 1 M for IL-10 production in bone marrow-derived dendritic cells). Also inhibits CDK19 in complex with cyclin C.

catalog number base :

6438

product keywords :

BRD6989 IL-10 production enhancers CDK8 inhibitors enhances inhibits Cytokines Cyclin-dependent Kinase 6438,

extended description :

Cdk8 inhibitor; enhances IL-10 production

chemical name text :

2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile

formula :

C 16 H 16 N 4

formula text :

C16H16N4

cas num :

642008-81-9

2020 USD :

129

2021 USD :

133 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage