6436/10 | Tocris Bioscience 6436/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6436/10

catalog :

6436/10

quantity :

10 mg (also 50 mg)

price :

235 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6436 - CY 09 C19H12F3NO3S2 CAS No. 1073612-91-5

product information

master code :

6436

SKU :

6436/10

product name :

CY 09

unit size :

10 mg (also 50 mg)

description :

NLRP3 inhibitor; active in vivo

target :

Inflammasomes Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

423.43

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CY 09 is a NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation. Displays therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes. Exhibits no activity for hERG (10 M).

top caption :

NLRP3 inhibitor; active in vivo

extended description :

NLRP3 inhibitor; active in vivo

chemical name text :

4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid

formula :

C19H12F3NO3S2

formula text :

C19H12F3NO3S2

cas num :

1073612-91-5

USD :

235 USD

product details :

NLRP3 inhibitor; active in vivo

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage