GSK 1016790A | Tocris Bioscience 6433 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 1016790A

catalog :

6433

quantity :

10 mg (also 50 mg)

price :

207 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6433

SKU :

6433/10

product name :

GSK 1016790A

description :

Potent TRPV4 agonist; active in vivo

target :

TRPV Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

655.61

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent TRPV4 agonist; elicits Ca2+ influx in human and mouse TRPV4-expressing HEK cells (EC50 values of 2.1 and 18 nM, respectively). Enhances insulin mRNA expression. Increases ERK1/2 phosphorylation and NO production. Exhibits no activity at TRPM8 and TRPA1 (20 M) channels. Induces bladder overactivity in TRPV4+/+ mice.

catalog number base :

6433

product keywords :

GSK1016790A trpv4 transient receptor potential channels potent selective agonists agonism activators vanilloid TRPV 6433,

extended description :

Potent TRPV4 agonist; active in vivo

chemical name text :

N-[(1S)-1-[[4-[(2S)-2-[[(2,4-Dichlorophenyl)sulfonyl]amino]-3-hydroxy-1-oxopropyl]-1-piperazinyl]carbonyl]-3-methylbutyl]benzo[b]thiophene-2-carboxamide

formula :

C 28 H 32 Cl 2 N 4 O 6 S 2

formula text :

C28H32Cl2N4O6S2

cas num :

942206-85-1

2020 USD :

199

2021 USD :

207 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage