6430/5 | Tocris Bioscience 6430/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6430/5

catalog :

6430/5

quantity :

5 mg (also 25 mg)

price :

96 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6430 - Takinib C18H18N4O2 CAS No. 1111556-37-6

product information

master code :

6430

SKU :

6430/5

product name :

Takinib

unit size :

5 mg (also 25 mg)

description :

Potent and selective TAK1/MAP3K7 kinase inhibitor

target :

Other Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

322.37

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Takinib is a potent and selective TAK1/MAP3K7 kinase inhibitor (IC50 = 8.2-9.5 nM). Selective for TAK1 over IRAK4, IRAK1, GCK, CLK2 and MINK1 (IC50 values = 120, 390, 430, 430 and 1900 nM, respectively). Demonstrates weak inhibition at Src and Yes1. Exhibits no inhibition of MAP2K or other MAP3K family members. Induces apoptosis following TNF- stimulation in in vitro models of rheumatoid arthritis and metastatic breast cancer.

top caption :

Potent and selective TAK1/MAP3K7 kinase inhibitor

extended description :

Potent and selective TAK1/MAP3K7 kinase inhibitor

chemical name text :

N1-(1-Propyl-1H-benzimidazol-2-yl)-1,3-benzenedicarboxamide

formula :

C18H18N4O2

formula text :

C18H18N4O2

cas num :

1111556-37-6

USD :

96 USD

product details :

Potent and selective TAK1/MAP3K7 kinase inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage