6426/5 | Tocris Bioscience 6426/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6426/5

catalog :

6426/5

quantity :

5 mg (also 25 mg)

price :

198 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6426 - PSEM 89S C16H22N2O3.CF3CO2H CAS No. 1336913-03-1

product information

master code :

6426

SKU :

6426/5

product name :

PSEM 89S

unit size :

5 mg (also 25 mg)

description :

PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist

target :

PSEMs

category :

Small Molecules

purity :

98%

observed molecular weight :

404.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PSEM 89S is a PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist (EC50 values are 3.4 and 2.2 M, respectively). Activates cortical neurons expressing PSAML141F,Y115F-5-HT3 chimeric ion channels and inhibits activity of neurons expressing PSAML141F-GlyR in vitro . Silences hypothalamic AGRP neurons transfected with PSAML141F-GlyR chimeric ion channels in mice in vivo , leading to suppression of feeding. Brain penetrant. . Plasmid vectors for the transfection of cells with PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 are available from Addgene.

top caption :

PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist

extended description :

PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist

chemical name text :

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate

formula :

C16H22N2O3.CF3CO2H

formula text :

C16H22N2O3.CF3CO2H

cas num :

1336913-03-1

USD :

198 USD

product details :

PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage