product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
6407/10
catalog :
6407/10
quantity :
10 mg (also 50 mg)
price :
55 USD
more info or order :
citations: 2
Reference
Jiang T, Li A, Lin C, Chiu C, Cho J, Reid B, et al. Global feather orientations changed by electric current. iScience. 2021;24:102671 pubmed publisher
Lin T, Lai K, Lee A, Chang C, Liu C, Chung C. Novel Antrodia cinnamomea Extract Reduced Cancer Stem-Like Phenotype Changes and Resensitized KRAS-Mutant Colorectal Cancer via a MicroRNA-27a Pathway. Cancers (Basel). 2019;11: pubmed publisher
image
image 1 :
Tocris Bioscience 6407/10 image 1
Cat.No. 6407 - Fendiline Hydrochloride C23H25N.HCl CAS No. 13636-18-5
product information
master code :
6407
SKU :
6407/10
product name :
Fendiline Hydrochloride
unit size :
10 mg (also 50 mg)
description :
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
target :
Ras GTPase Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
351.91
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Fendiline Hydrochloride is a K-Ras inhibitor. Selectively inhibits K-Ras localization to the plasma membrane (IC50 = 9.64 M). Blocks proliferation of cancer cell lines expressing oncogenic mutant K-Ras. Also inhibits L-type calcium channels (IC50 = 17 M).
top caption :
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
extended description :
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
chemical name text :
N-(3,3-Diphenylpropyl)- -methylbenzylamine hydrochloride
formula :
C23H25N.HCl
formula text :
C23H25N.HCl
cas num :
13636-18-5
USD :
55 USD
product details :
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
storage :
Store at +4░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK