SKA 121 | Tocris Bioscience 6398 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SKA 121

catalog :

6398

quantity :

25 mg

price :

349 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6398 - SKA 121 C12H10N2O CAS No. 1820708-73-3

product information

brand :

Tocris

master code :

6398

SKU :

6398/25

product name :

SKA 121

description :

Positive allosteric modulator of KCa3.1 (IK) channels

target :

Ca2+-Activated Potassium Channel Activators

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

198.23

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Positive allosteric modulator of KCa3.1 (intermediate-conductance Ca2+-activated potassium) channels (EC50 = 109 nM). Displays 40-fold selectivity for KCa3.1 over KCa2.3, and 200 to 400-fold selectivity over KV and NaV channels. Potentiates bradykinin-induced vasodilation ex vivo . Lowers mean arterial blood pressure in normotensive and hypertensive mice.

catalog number base :

6398

product keywords :

SKA121 calcium sensitive activated potassium channel positive allosteric modulators modulates kca3.1 intermediate conductance SK4 IK blood pressure vasodilation Ca2+-Activated Potassium Channels 6398,

extended description :

Positive allosteric modulator of KCa3.1 (IK) channels

chemical name text :

5-Methylnaphth[2,1-d]oxazol-2-amine

formula :

C 12 H 10 N 2 O

formula text :

C12H10N2O

cas num :

1820708-73-3

2020 USD :

349

2021 USD :

349 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage