CD38 inhibitor 78c CD38 inhibitor 78c CD38 inhibitor 78c CD3 | Tocris Bioscience 6391 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CD38 inhibitor 78c CD38 inhibitor 78c CD38 inhibitor 78c CD3

catalog :

6391

quantity :

5 mg

price :

209 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6391 - CD38 inhibitor 78cCD38 inhibitor 78cCD38 inhibitor 78cCD38 inhibitor 78c C22H27N3O3S CAS No. 1700637-55-3

product information

brand :

Tocris

master code :

6391

SKU :

6391/5

product name :

CD38 inhibitor 78c CD38 inhibitor 78c CD38 inhibitor 78c CD3

description :

Potent CD38 inhibitor; active in vivo

target :

Hydrolase Inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

413.54

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent CD38 (ADP ribosyl cyclase/hydrolase) inhibitor (IC50 values are 1.9 and 7.3 nM at mouse and human CD38, respectively). Catalyzes breakdown of NAD to nicotinamide and ADPR, and hydrolyzes NAADP to adenosine-5 -O-diphosphoribose phosphate. Elevates NAD+ levels 5-fold in liver and 1.2-fold in muscle of diet-induced obese (DIO) C57Bl6 mice. Also prevents age-related NAD+ decline in mice. Improves glucose intolerance, cardiac function and improves physiological and metabolic parameters in old mice.

catalog number base :

6391

product keywords :

CD38 inhibitor 78c Potent CD38 inhibitors inhibits ADP ribosyl cyclases CD157 ribosyl hydrolases Other Hydrolases 6391,

extended description :

Potent CD38 inhibitor; active in vivo

chemical name text :

4-[[trans-4-(2-Methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)-2(1H)-quinolinone

formula :

C 22 H 27 N 3 O 3 S

formula text :

C22H27N3O3S

cas num :

1700637-55-3

2020 USD :

209

2021 USD :

209 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage