6370/10 | Tocris Bioscience 6370/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6370/10

catalog :

6370/10

quantity :

10 mg

price :

163 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Grobben Y, Uitdehaag J, Willemsen Seegers N, Tabak W, de Man J, Buijsman R, et al. Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158. J Struct Biol X. 2020;4:100014 pubmed publisher
Grobben Y, Willemsen Seegers N, Uitdehaag J, de Man J, van Groningen J, Friesen J, et al. High-Throughput Fluorescence-Based Activity Assay for Arginase-1. SLAS Discov. 2020;25:1018-1025 pubmed publisher

product information

master code :

6370

SKU :

6370/10

product name :

Nor NOHA monoacetate

unit size :

10 mg

description :

Arginase inhibitor

target :

Hydrolase Inhibitors

category :

Small Molecules

observed molecular weight :

236.23

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Nor NOHA monoacetate is a reversible, competitive arginase inhibitor (IC50 = 2 M). Exhibits 10-fold selectivity for human type II arginase over type I. Enhances the effect of acetylcholine on isolated aortic and mesenteric arterial rings. Inhibits growth of lung carcinoma implants in mice.

top caption :

Arginase inhibitor

extended description :

Arginase inhibitor

chemical name text :

(2S)-2-Amino-4-[[(hydroxyamino)iminomethyl]amino]butanoic acid monoacetate

formula :

C5H12N4O3.C2H4O2

formula text :

C5H12N4O3.C2H4O2

cas num :

2250019-93-1

USD :

163 USD

product details :

Arginase inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage