GNE 9278 | Tocris Bioscience 6369 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GNE 9278

catalog :

6369

quantity :

10 mg (also 50 mg)

price :

225 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6369

SKU :

6369/10

product name :

GNE 9278

description :

Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

target :

NMDA Receptor Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

429.54

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Positive allosteric modulator of NMDA receptors. Potentiates NMDA receptors containing GluN2A, 2B, 2C and 2D subunits (EC50 values are 0.74, 3.07, 0.47 and 0.32 M in a Ca2+ influx assay, respectively). Binds within the transmembrane domain and displays preference for agonist-bound NMDA receptors. Slows receptor deactivation and enhances the potency of glutamate and glycine.

catalog number base :

6369

product keywords :

GNE9278 NMDA receptor positive allosteric modulators modulates PAM GluN2A GluN2B GluN2C GluN2D NMDA Receptors 6369,

extended description :

Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

chemical name text :

4-Cyclohexyl-N-(7-hydroxy-5-methyl-2-propyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)benzenesulfonamide

formula :

C 21 H 27 N 5 O 3 S

formula text :

C21H27N5O3S

cas num :

901230-11-3

2020 USD :

216

2021 USD :

225 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage