6369/10 | Tocris Bioscience 6369/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6369/10

catalog :

6369/10

quantity :

10 mg (also 50 mg)

price :

289 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6369 - GNE 9278 C21H27N5O3S CAS No. 901230-11-3

product information

master code :

6369

SKU :

6369/10

product name :

GNE 9278

unit size :

10 mg (also 50 mg)

description :

Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

target :

NMDA Receptor Modulators

category :

Small Molecules

purity :

98%

observed molecular weight :

429.54

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

GNE 9278 is a positive allosteric modulator of NMDA receptors. Potentiates NMDA receptors containing GluN2A, 2B, 2C and 2D subunits (EC50 values are 0.74, 3.07, 0.47 and 0.32 M in a Ca2+ influx assay, respectively). Binds within the transmembrane domain and displays preference for agonist-bound NMDA receptors. Slows receptor deactivation and enhances the potency of glutamate and glycine .

top caption :

Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

extended description :

Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

chemical name text :

4-Cyclohexyl-N-(7-hydroxy-5-methyl-2-propyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)benzenesulfonamide

formula :

C21H27N5O3S

formula text :

C21H27N5O3S

cas num :

901230-11-3

USD :

289 USD

product details :

Positive allosteric modulator of NMDA receptors; acts in transmembrane domain

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage