Z 944 | Tocris Bioscience 6367 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Z 944

catalog :

6367

quantity :

10 mg (also 50 mg)

price :

223 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6367

SKU :

6367/10

product name :

Z 944

description :

CaV3.x blocker

target :

Voltage-gated Calcium Channel Blockers

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

383.89

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective T-type Ca2+ channel blocker (IC50 values are 50 to 160 nM for hCav3.1, hCav3.2 and hCav3.3). Exhibits 50 to 600 fold selectivity for Cav3.x channels over related ion channels (Cav1.2, hERG and Nav1.5). Has no effect on action potential properties in isolated heart Purkinje fibers and no adverse effects on ECG parameters in vivo . Exhibits anti-seizure effects in animal models.

catalog number base :

6367

product keywords :

Z944 T-type calcium channel blockers anti-epileptic in vivo Cav3.1 Cav3.2 Cav3.3 Ca2+ blocks Cav3.x Channels 6367,

extended description :

CaV3.x blocker

chemical name text :

4-[[(3-Chloro-5-fluorobenzoyl)amino)methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide

formula :

C 19 H 27 ClFN 3 O 2

formula text :

C19H27ClFN3O2

cas num :

1199236-64-0

2020 USD :

214

2021 USD :

223 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage