Atovaquone | Tocris Bioscience 6358 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Atovaquone

catalog :

6358

quantity :

10 mg (also 50 mg)

price :

57 USD

product information

brand :

Tocris

master code :

6358

SKU :

6358/10

product name :

Atovaquone

description :

Inhibits complex III of mitochondrial electron transport chain in parasites

target :

Oxidative Phosphorylation Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

366.84

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Broad spectrum antiparasitic and antipneumocystic compound. Inhibits bc1 complex (complex III) of mitochondrial electron transport chain (EC50 = 0.26 M), causing cell death in Plasmodium yoelii infected erythrocytes. Also inhibits DHODH. Also exhibits anti-MERS-CoV activity in Vero cells in vitro (IC50 = 0.72 M).

catalog number base :

6358

product keywords :

atovaquone antimalarial antiparasitic mitochondria respiration inhibitors inhibits DHODH dihydroorotate dehydrogenase COVID-19 SARS-CoV-2 severe acute respiratory syndrome MERS Oxidative Phosphorylation Dihyroorotate Dehydrogenase Antimalarials COVID-19 Coronavirus 6358,

extended description :

Inhibits complex III of mitochondrial electron transport chain in parasites

chemical name text :

2-[trans-4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione

formula :

C 22 H 19 ClO 3

formula text :

C22H19ClO3

cas num :

95233-18-4

2020 USD :

2021 USD :

57 USD

storage :

Store at -20°C