product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Atovaquone
catalog :
6358/10
quantity :
10 mg (also 50 mg)
price :
55 USD
more info or order :
product information
brand :
Tocris
SKU :
6358/10
product name :
Atovaquone
unit sizes :
10 mg (also 50 mg)
description :
Inhibits complex III of mitochondrial electron transport chain in parasites
target :
Oxidative Phosphorylation Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
366.84
details of functionality :
Broad spectrum antiparasitic and antipneumocystic compound. Inhibits bc1 complex (complex III) of mitochondrial electron transport chain (EC50 = 0.26 M), causing cell death in Plasmodium yoelii infected erythrocytes. Also inhibits DHODH. Also exhibits anti-MERS-CoV activity in Vero cells in vitro (IC50 = 0.72 M).
catalog number base :
6358
extended description :
Inhibits complex III of mitochondrial electron transport chain in parasites
chemical name text :
2-[trans-4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione
formula :
C 22 H 19 ClO 3
formula text :
C22H19ClO3
cas num :
95233-18-4
USD :
55 USD
product details :
Inhibits complex III of mitochondrial electron transport chain in parasites
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK