PF 05190457 | Tocris Bioscience 6350 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 05190457

catalog :

6350

quantity :

25 mg

price :

332 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6350

SKU :

6350/25

product name :

PF 05190457

description :

High affinity and selective ghrelin receptor inverse agonist

target :

Ghrelin Receptor Inverse Agonists

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

512.67

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity and selective ghrelin receptor inverse agonist (Kd = 3 nM). Exhibits selectivity for ghrelin receptors over a panel of other targets. Increases intracellular Ca2+ concentration in and insulin secretion from human islets in vitro . Increases gastric afferent nerve activity in a rat ex vivo stomach preparation.

catalog number base :

6350

product keywords :

PF05190457 high affinity selective ghrelin inverse agonists agonism antagonists type II diabetes obesity Ghrelin Receptors 6350,

extended description :

High affinity and selective ghrelin receptor inverse agonist

chemical name text :

1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone

formula :

C 29 H 32 N 6 O S

formula text :

C29H32N6OS

cas num :

1334782-79-4

2020 USD :

319

2021 USD :

332 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage