6350/5 | Tocris Bioscience 6350/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6350/5

catalog :

6350/5

quantity :

5 mg (also 25 mg)

price :

109 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Qin J, Cai Y, Xu Z, Ming Q, Ji S, Wu C, et al. Molecular mechanism of agonism and inverse agonism in ghrelin receptor. Nat Commun. 2022;13:300 pubmed publisher

image

image 1 :

Cat.No. 6350 - PF 05190457 C29H32N6OS CAS No. 1334782-79-4

product information

master code :

6350

SKU :

6350/5

product name :

PF 05190457

unit size :

5 mg (also 25 mg)

description :

High affinity and selective ghrelin receptor inverse agonist

target :

Ghrelin Receptor Inverse Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

512.67

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PF 05190457 is a high affinity and selective ghrelin receptor inverse agonist (Kd = 3 nM). Exhibits selectivity for ghrelin receptors over a panel of other targets. Increases intracellular Ca2+ concentration in and insulin secretion from human islets in vitro . Increases gastric afferent nerve activity in a rat ex vivo stomach preparation.

top caption :

High affinity and selective ghrelin receptor inverse agonist

extended description :

High affinity and selective ghrelin receptor inverse agonist

chemical name text :

1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone

formula :

C29H32N6OS

formula text :

C29H32N6OS

cas num :

1334782-79-4

USD :

109 USD

product details :

High affinity and selective ghrelin receptor inverse agonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage