Pelitinib | Tocris Bioscience 6349 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Pelitinib

catalog :

6349

quantity :

25 mg

price :

347 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6349

SKU :

6349/25

product name :

Pelitinib

description :

Potent and irreversible EGFR inhibitor; orally bioavailable

target :

EGF Receptor Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

97%

observed molecular weight :

467.92

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent irreversible EGFR inhibitor (IC50 = 20-80 nM). Selective for EGFR over Src, MEK/ERK, erbB2, Raf, c-Met and Cdk4 (IC50 values are 282, 800, 1255, 3353, 4100 and 20,000). Inhibits the growth of tumors overexpressing EGFR in vivo . Orally bioavailable.

catalog number base :

6349

product keywords :

EKB-569 orally active potent irreversible EGFR inhibitors inhibits ErbB-1 active in vivo EKB-569 EGFR 6349,

extended description :

Potent and irreversible EGFR inhibitor; orally bioavailable

chemical name text :

(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide

formula :

C 24 H 23 ClFN 5 O 2

formula text :

C24H23ClFN5O2

cas num :

257933-82-7

2020 USD :

385

2021 USD :

347 USD

alt names :

EKB-569

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage