PF 04991532 | Tocris Bioscience 6345 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 04991532

catalog :

6345

quantity :

25 mg

price :

252 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6345 - PF 04991532 C18H19F3N4O3 CAS No. 1215197-37-7

product information

brand :

Tocris

master code :

6345

SKU :

6345/25

product name :

PF 04991532

description :

Potent hepatoselective glucokinase activator

target :

Glucokinase/GCK

category :

Small Molecules

unit size :

25 mg

main entrez gene id :

2645

purity :

98%

observed molecular weight :

396.36

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent hepatoselective glucokinase activator (EC50 = 90 nM). Exhibits 50-fold liver to pancreas ratio of tissue distribution. Reduces fasting and postprandial glucose levels with no hypoglycemia in a rat diabetes model.

catalog number base :

6345

product keywords :

PF04991532 glucokinase activators activates potent antidiabetic Hexokinases Enzyme Substrates/ Activators 6345, kinasesphosphatases, glycobiologyenzymes, GK, Hexokinase 4, Hexokinase D, Hexokinase IV, HKIV, HK IV, HK 4, non-insulin dependent diabetes mellitus, NIDDM, maturity onset diabetes of the young, type 2, MODY2, persistent hyperinsulinemic hypoglycemia of in

extended description :

Potent hepatoselective glucokinase activator

chemical name text :

6-[[(2S)-3-Cyclopentyl-1-oxo-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propyl]amino]-3-pyridinecarboxylic acid

formula :

C 18 H 19 F 3 N 4 O 3

formula text :

C18H19F3N4O3

cas num :

1215197-37-7

2020 USD :

279

2021 USD :

252 USD

alt names :

EC 2.7.1, EC 2.7.1.2, FGQTL3, GCK, GK, GLK, glucokinase (hexokinase 4), hexokinase-4, Hexokinase-D, HHF3, HK4, HK4pancreatic isozyme, HKIV, HXKP, LGLK, maturity onset diabetes of the young 2, MODY2

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage