6343/10 | Tocris Bioscience 6343/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6343/10

catalog :

6343/10

quantity :

10 mg (also 50 mg)

price :

96 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rojo Arreola L, Long T, Asarnow D, Suzuki B, Singh R, Caffrey C. Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasis. PLoS ONE. 2014;9:e87594 pubmed publisher

product information

master code :

6343

SKU :

6343/10

product name :

Rosuvastatin calcium

unit size :

10 mg (also 50 mg)

description :

Potent HMG-CoA reductase inhibitor

target :

HMG-CoA Reductase Inhibitors

category :

Small Molecules

purity :

99%

observed molecular weight :

500.57

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Rosuvastatin calcium is a potent HMG-CoA reductase inhibitor (IC50 = 5.4 nM). Inhibits cholesterol synthesis in rat hepatocytes in vitro and in vivo . Reduces plasma LDL cholesterol levels. Enhances lentiviral transduction of natural killer cells. Orally bioavailable.

top caption :

Potent HMG-CoA reductase inhibitor

extended description :

Potent HMG-CoA reductase inhibitor

chemical name text :

(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl])-3,5-dihydroxyhept-6-enoic acid hemicalcium salt

formula :

C22H27FN3O6S. Ca

formula text :

C22H27FN3O6S.?Ca

cas num :

147098-20-2

USD :

96 USD

product details :

Potent HMG-CoA reductase inhibitor

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage