6332/10 | Tocris Bioscience 6332/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6332/10

catalog :

6332/10

quantity :

10 mg

price :

204 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Jurek B, Denk L, Sch xe4 fer N, Salehi M, Pandamooz S, Haerteis S. Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping. Front Cell Neurosci. 2022;16:1000538 pubmed publisher
Li X, Matsuura T, Xue M, Chen Q, Liu R, Lu J, et al. Oxytocin in the anterior cingulate cortex attenuates neuropathic pain and emotional anxiety by inhibiting presynaptic long-term potentiation. Cell Rep. 2021;36:109411 pubmed publisher
Barrett L, Nunez J, Zhang X. Oxytocin activation of paraventricular thalamic neurons promotes feeding motivation to attenuate stress-induced hypophagia. Neuropsychopharmacology. 2021;46:1045-1056 pubmed publisher
Ando M, Hayashi Y, Hitomi S, Shibuta I, Furukawa A, Oto T, et al. Oxytocin-Dependent Regulation of TRPs Expression in Trigeminal Ganglion Neurons Attenuates Orofacial Neuropathic Pain Following Infraorbital Nerve Injury in Rats. Int J Mol Sci. 2020;21: pubmed publisher

product information

master code :

6332

SKU :

6332/10

product name :

Atosiban

unit size :

10 mg

description :

Potent oxytocin receptor antagonist

target :

Oxytocin Receptor Antagonists

category :

Peptides

purity :

98%

observed molecular weight :

994.19

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Atosiban is a potent oxytocin receptor (OTR) antagonist. Inhibits oxytocin-induced increase in Ca2+ concentration in myometrial cells in vitro (IC50 = 5 nM) Activates NF- B and MAPK pathways in human amnion via G i signaling, resulting in pro-inflammatory effects. Inhibits oxytocin-induced uterine contractions in vivo and in vitro . Effective in a rat preterm labor model.

top caption :

Potent oxytocin receptor antagonist

extended description :

Potent oxytocin receptor antagonist

formula :

C43H67N11O12S2

formula text :

C43H67N11O12S2

cas num :

90779-69-4

USD :

204 USD

product details :

Potent oxytocin receptor antagonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage