6324/10 | Tocris Bioscience 6324/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6324/10

catalog :

6324/10

quantity :

10 mg (also 50 mg)

price :

215 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Relic B, Deroyer C, Malaise O, Plener Z, Gillet P, de Seny D, et al. TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells. Biochem J. 2021;478:3145-3155 pubmed publisher

image

image 1 :

Cat.No. 6324 - Autophinib C14H11ClN6O3 CAS No. 1644443-47-9

product information

master code :

6324

SKU :

6324/10

product name :

Autophinib

unit size :

10 mg (also 50 mg)

description :

Potent VPS34 inhibitor

target :

Autophagy-related Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

346.73

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Autophinib is a potent VPS34 (class III PI 3-kinase) inhibitor (IC50 = 19 nM). Inhibits starvation- and Rapamycin -induced autophagy (IC50 values = 40 and 90 nM, respectively).

top caption :

Potent VPS34 inhibitor

extended description :

Potent VPS34 inhibitor

chemical name text :

6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-pyrimidinamine

formula :

C14H11ClN6O3

formula text :

C14H11ClN6O3

cas num :

1644443-47-9

USD :

215 USD

product details :

Potent VPS34 inhibitor

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage