10-Cl-BBQ | Tocris Bioscience 6321 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

10-Cl-BBQ

catalog :

6321

quantity :

25 mg

price :

246 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6321

SKU :

6321/25

product name :

10-Cl-BBQ

description :

Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable

target :

Aryl Hydrocarbon Receptor Agonists

category :

Small Molecules

unit size :

25 mg

purity :

97%

observed molecular weight :

304.73

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent aryl hydrocarbon receptor (AhR) agonist, discovered as a screening hit (IC50 = 2.6 nM). Directly binds CD4+ T cells to induce AhR-dependent Tregs. Suppresses IL-17 production and prevents insulitis in NOD mice. In vivo half llife ~ 2 hours, orally bioavailable.

catalog number base :

6321

product keywords :

Potent aryl hydrocarbon receptor AhR agonists antagonism Tregs insulitis orally bioavailable Aryl Hydrocarbon Receptors 6321,

extended description :

Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable

chemical name text :

10-Chloro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one

formula :

C 18 H 9 ClN 2 O

formula text :

C18H9ClN2O

cas num :

23982-76-5

2020 USD :

236

2021 USD :

246 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage