product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
6305/100
catalog :
6305/100
quantity :
100 mg
price :
62 USD
more info or order :
citations: 1
Reference
Calderon A, Soldan S, De Leo A, Deng Z, Frase D, Anderson E, et al. Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism. Oncotarget. 2020;11:4224-4242 pubmed publisher
image
image 1 :
Tocris Bioscience 6305/100 image 1
Cat.No. 6305 - Lenalidomide C13H13N3O3 CAS No. 191732-72-6
product information
master code :
6305
SKU :
6305/100
product name :
Lenalidomide
unit size :
100 mg
description :
Cereblon binder; induces ubiquitination and degradation of CK1 by E3 ubiquitin ligase
target :
Ubiquitin Ligase (E3) Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
259.26
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Lenalidomide is a thalidomide analog. Immune modulatory drug and cereblon binding compound. Induces ubiquitination and degradation of casein kinase (CK) 1 by the E3 ubiquitin ligase CRL4CRBN. Also TNF- inhibitor and angiogenesis inhibitor. Promotes degradation of transcription factor SALL4.
top caption :
Cereblon binder; induces ubiquitination and degradation of CK1 by E3 ubiquitin ligase
extended description :
Cereblon binder; induces ubiquitination and degradation of CK1 by E3 ubiquitin ligase
chemical name text :
3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
formula :
C13H13N3O3
formula text :
C13H13N3O3
cas num :
191732-72-6
USD :
62 USD
product details :
Cereblon binder; induces ubiquitination and degradation of CK1 by E3 ubiquitin ligase
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK