Pomalidomide | Tocris Bioscience 6302 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Pomalidomide

catalog :

6302

quantity :

10 mg (also 50 mg)

price :

150 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

6302

SKU :

6302/10

product name :

Pomalidomide

description :

Cereblon binder; also TNF- inhibitor and antiangiogenic

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

273.24

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent TNF- inhibitor (IC50 = 13 nM). Also potently inhibits IL-2 (EC50 = 8 nM). Thalidomide derivative. Binds cereblon and inhibits its ubiquitination. Exhibits antiproliferative effects in a Namalwa lymphoma cell line. Antiangiogenic. Promotes degradation of transcription factor SALL4.

catalog number base :

6302

product keywords :

Pomalidomide TNFa TNFalpha TNF Inhibitors inhibits IL-2 thalidomide cereblon binder ubiquitination antiproliferative antiangiogenic lymphoma SALL4 CELMoD E3 ligase modulators immunomodulators immunomodulatory imide IMiDs Ubiquitin E3 Ligases Cytokines Antiangiogenics Other Transcription Factors Molecular Glues 6302, E3 Ligase

extended description :

Cereblon binder; also TNF- inhibitor and antiangiogenic

chemical name text :

4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

formula :

C 13 H 11 N 3 O 4

formula text :

C13H11N3O4

cas num :

19171-19-8

2020 USD :

144

2021 USD :

150 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage