6302/10 | Tocris Bioscience 6302/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6302/10

catalog :

6302/10

quantity :

10 mg (also 50 mg)

price :

190 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Bondeson D, Mullin Bernstein Z, Oliver S, Skipper T, Atack T, Bick N, et al. Systematic profiling of conditional degron tag technologies for target validation studies. Nat Commun. 2022;13:5495 pubmed publisher

image

image 1 :

Cat.No. 6302 - Pomalidomide C13H11N3O4 CAS No. 19171-19-8

product information

master code :

6302

SKU :

6302/10

product name :

Pomalidomide

unit size :

10 mg (also 50 mg)

description :

Cereblon binder; also TNF- inhibitor and antiangiogenic

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

273.24

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Pomalidomide is a potent TNF- inhibitor (IC50 = 13 nM). Also potently inhibits IL-2 (EC50 = 8 nM). Thalidomide derivative. Binds cereblon and inhibits its ubiquitination. Exhibits antiproliferative effects in a Namalwa lymphoma cell line. Antiangiogenic. Promotes degradation of transcription factor SALL4.

top caption :

Cereblon binder; also TNF- inhibitor and antiangiogenic

extended description :

Cereblon binder; also TNF- inhibitor and antiangiogenic

chemical name text :

4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

formula :

C13H11N3O4

formula text :

C13H11N3O4

cas num :

19171-19-8

USD :

190 USD

product details :

Cereblon binder; also TNF- inhibitor and antiangiogenic

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage