6298/10 | Tocris Bioscience 6298/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6298/10

catalog :

6298/10

quantity :

10 mg (also 50 mg)

price :

148 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Fujiwara Y, Torphy R, Sun Y, Miller E, Ho F, Borcherding N, et al. The GPR171 pathway suppresses T cell activation and limits antitumor immunity. Nat Commun. 2021;12:5857 pubmed publisher

image

image 1 :

Cat.No. 6298 - MS 21570 C10H11N3S2 CAS No. 65373-29-7

product information

master code :

6298

SKU :

6298/10

product name :

MS 21570

unit size :

10 mg (also 50 mg)

description :

GPR171 antagonist

target :

GPR171 Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

237.34

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MS 21570 is a GPR171 antagonist (IC50 = 220 nM). Inhibits BigLEN (Cat.No. 6304) mediated increases in [35S]GTP S binding in hypothalamic membranes and hyperpolarization of basolateral amygdala pyramidal neurons. Reduces anxiety-like behavior and fear conditioning in mice.

top caption :

GPR171 antagonist

extended description :

GPR171 antagonist

chemical name text :

N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine

formula :

C10H11N3S2

formula text :

C10H11N3S2

cas num :

65373-29-7

USD :

148 USD

product details :

GPR171 antagonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage