AP 20187 | Tocris Bioscience 6297 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AP 20187

catalog :

6297

quantity :

5 mg

price :

335 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6297 - AP 20187 C82H107N5O20 CAS No. 195514-80-8

product information

brand :

Tocris

master code :

6297

SKU :

6297/5

product name :

AP 20187

description :

Chemical inducer of protein dimerization; active in vivo

target :

Protein Dimerizers

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

1482.77

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Chemical inducer of dimerization (CID) for use in FKBP fusion protein systems. Induces apoptosis in cells expressing fusion proteins consisting of FKBPF36V and the intracellular domain of the Fas receptor, Fas-associated death domain (FADD) or a caspase. Selective for FKBPF36V-Fas fusion proteins over wild-type FKBP. Induces apoptosis of senescent cells expressing caspase-8-FKBP fusion proteins under the control of an Ink4a promoter. Active in vivo .

catalog number base :

6297

product keywords :

AP20187 Chemical protein dimerizer caspases 9 induces inducers apoptosis FKBPF36V fusion FK506-binding protein CID Protein Dimerizers 6297,

extended description :

Chemical inducer of protein dimerization; active in vivo

chemical name text :

2,2 -[[2-[(Dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[(1R)-3-(3,4-dimethoxyphenyl)propylidene]]] bis[1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate]

formula :

C 82 H 107 N 5 O 20

formula text :

C82H107N5O20

cas num :

195514-80-8

2020 USD :

335

2021 USD :

335 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage