6297/5 | Tocris Bioscience 6297/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6297/5

catalog :

6297/5

quantity :

5 mg

price :

439 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 6297 - AP 20187 C82H107N5O20 CAS No. 195514-80-8

product information

master code :

6297

SKU :

6297/5

product name :

AP 20187

unit size :

5 mg

description :

Chemical inducer of protein dimerization; active in vivo

target :

Protein Dimerizers

category :

Small Molecules

purity :

98%

observed molecular weight :

1482.77

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AP 20187 is a chemical inducer of dimerization (CID) for use in FKBP fusion protein systems. Induces apoptosis in cells expressing fusion proteins consisting of FKBPF36V and the intracellular domain of the Fas receptor, Fas-associated death domain (FADD) or a caspase. Selective for FKBPF36V-Fas fusion proteins over wild-type FKBP. Induces apoptosis of senescent cells expressing caspase-8-FKBP fusion proteins under the control of an Ink4a promoter. Active in vivo . . For more information about how AP 20187 may be used, see our protocol .

top caption :

Chemical inducer of protein dimerization; active in vivo

extended description :

Chemical inducer of protein dimerization; active in vivo

chemical name text :

2,2 -[[2-[(Dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[(1R)-3-(3,4-dimethoxyphenyl)propylidene]]] bis[1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate]

formula :

C82H107N5O20

formula text :

C82H107N5O20

cas num :

195514-80-8

USD :

439 USD

product details :

Chemical inducer of protein dimerization; active in vivo

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage